Cutaneous Langerhans Cell Histiocytosis Masquerades as a Chalazion in a Toddler Patient

Chen YH, Huang PW and Tsai YJ

Department of Ophthalmology, Linkou Chang Gung Memorial Hospital, Taiwan
College of Medicine, Chang Gung University, Taiwan
Department of Ophthalmology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Taiwan

^*Correspondance to: Yueh-Ju Tsai 

 PDF  Full Text Case Report | Open Access

Abstract:

Background: Langerhans Cell Histiocytosis (LCH) is an uncommon disease that involves the excessive growth of histiocytes, and is more prevalent among children population. LCH can impact various organs with diverse clinical presentations. However, the ophthalmic presentation of LCH had been scarcely reported.
Case Report: In this article, we report a unique case of a 17-month-old girl who presented with a non-resolving eyelid chalazion for 2 months, follows up by disseminated skin and left ulna bony involvement. The biopsy of eyelid lesion confirmed the diagnosis of LCH. The lesions regressed without evidence of recurrence after systemic chemotherapy.
Conclusion: Although LCH of the eyelid is uncommon, it is crucial to consider it as a potential diagnosis for nodular lesions on the eyelid.

Keywords:

Langerhans cell histiocytosis; Pediatric; Chalazion; BRAF mutation

Cite the Article:

Chen YH, Huang PW, Tsai YJ. Cutaneous Langerhans Cell Histiocytosis Masquerades as a Chalazion in a Toddler Patient. World J Surg Surgical Res. 2023; 6: 1507..