Journal Basic Info

  • Impact Factor: 1.989**
  • H-Index: 6
  • ISSN: 2637-4625
  • DOI: 10.25107/2637-4625
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Hand Surgery
  •  Hepatology
  •  Pediatric Surgery
  •  Oral & Maxillofacial Surgery
  •  Dental Surgery
  •  Surgery & Surgical Research
  •  General Surgery
  •  Gastroenterological Surgery

Abstract

Citation: World J Surg Surg Res. 2019;2(1):1182.DOI: 10.25107/2637-4625.1182

Extended High Hilar Resection and Enlarged Hepatic Portal Enterostomy in the Treatment of Hilar Cholangiocarcinoma

Abdul Qahar Saleh*, Chen Yu-Xin, Ning Shang Lei, Guo Ling Yu and Habibullah Fitrat

Department of Hepatobiliary, Qilu Hospital of Shandong University, China

*Correspondance to: Abdul Qahar Saleh 

 PDF  Full Text Review Article | Open Access

Abstract:

Background: Tertiary biliary radical reconstruction and biliary-enteric continuity restoration limits
the radical resection of hilar cholangiocarcinoma, because there are multiple biliary radicals in the
cut surface of liver and some of them are smaller than 1 mm to 2 mm. Enlarged anastomosis orifice
might delay the jaundice related to local recurrence which is the main cause of long-term morbidity
and mortality. We proposed extended high hilar resection and enlarged hepatic portal parenchymaenterostomy
for hilar cholangiocarcinoma.
Methods: Fifty-six patients of hepatic hilar cholangiocarcinoma were referred for surgical treatment
from March 2016 to March 2018. Duplex Ultrasonography (US), Computed Tomography (CT)
and/or Magnetic Resonance Cholangiopancreatography (MRCP) were applied to evaluate the range
of invasion and distant metastasis of tumors. Percutaneous Transhepatic Biliary Drainage (PTCD)
and bile refusion were performed on patients with Child Grade C, and a Total Bilirubin (TB) level
higher than 400 μmol/L and Child Grade B or above.
Results: Hepatic hilar resection and portal parenchyma-enterostomy was performed on 51 patients,
and stent enterostomy was carried out on 5 patients. Eleven patients underwent right hepatic artery
resection and partial resection of portal vein was performed on 4 patients. Combined right/or left
lobectomy with caudate lobectomy was carried out on 16 patients. The levels of serum Aspartate
Aminotransferase (AST) and Alanine Aminotransferase (ALT) decreased significantly. Icterus
was significantly improved and the serum TB level decreased postoperatively. Hepatic abscess
occurred in 3 patients. One patient with bile leakage died of pneumonia 2 months post operation.
The remaining patients recovered three months after operation to a life close to normal conditions.
Conclusion: Extended high hilar resection and enlarged hepatic portal enterostomy was applied for
the treatment of hilar cholangiocarcinoma patients and it had a positive outcome in many patients.

Keywords:

High hilar cholangiocarcinoma; Portal parenchyma enterostomy; AST; ALT

Cite the Article:

Saleh AQ, Yu-Xin C, Shang Lei N, Ling Yu G, Fitrat H. Extended High Hilar Resection and Enlarged Hepatic Portal Enterostomy in the Treatment of Hilar Cholangiocarcinoma. World J Surg Surgical Res. 2019; 2: 1182..

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