Surgical Outcomes in Patients with Disorders of Sex Development in Mofid Children’s Hospital, 2001-2014

Ahmad Khaleghnejad Tabari, Mohsen Rouzrokh, Leily Mohajerzadeh, Arameh Abbasianchavari, Sareh Pour Hassan, Saran Lotfollahzadeh and Khashayar Atqiaee

Pediatric Surgery Research Center, Research Institute for Children Health, Shahid Beheshti University of Medical Sciences, Iran

^*Correspondance to: Saran Lotfollahzadeh 

 PDF  Full Text Case Report | Open Access

Abstract:

Background: Disorders of Sex Development is a childhood and infantile anomaly affects not only the somatic growth; but also leading to stress and anxiety among parents who are seeking optimal treatments. Accordingly in this study the surgical outcomes in patients with Disorders of Sex Development in Mofid Children’s Hospital from 2001 to 2014 were determined.
Materials and Methods: In this retrospetive study children with Disorders of Sex Development in Mofid Children’s Hospital from 2001 to 2014 who met the eligibility criteria were included. Data were gathered by existing medical documents and were recorded in prepared checklist. The surgical outcomes were assessed with interview and clinical examination after announcement by hospital. The success and complication rate including external genitalia acceptable feature, vaginal stenosis in prepuberty period, intercourse problems during fertility period and gender dysphoria were determined by a multi-disciplinary team including Paediatric Surgeons, Paediatric endocrinologists and Psychologists.
Results: In the current study we have evaluated seventy two patients; 55 (76.38%) affected by Congenital Adrenal Hyperplasia, thirteen (18.05%) by Testicular Feminization, 2 (2.7%) by Ovotesticular Disorder and two case (2.7%) by Mixed Gonadal Dysgenesis. Most common type of applied surgery was Clithroplasty, Genitoplasty and Pull through Vaginoplasty (47 cases). Fifty nine patients (81.9%) had no surgical complications. All patients had good conditions at discharge and no mortality was registered. Three cases of Testicular Feminization (4.2%) Who Underwent pull trough colovaginoplasty were married.
Conclusion: According to our findings, surgical outcomes in cases of Disorders of Sex Development are relatively good and satisfactory. However long-term follow-up study is required to determine the final outcomes especially for marital and sexual issues.

Keywords:

Clitoroplasty; MixGonadal; Ovotestis; Vaginoplasty

Cite the Article:

Tabari AK, Rouzrokh M, Mohajerzadeh L, Abbasianchavari A, Hassan SP, Lotfollahzadeh S, et al. Surgical Outcomes in Patients with Disorders of Sex Development in Mofid Children’s Hospital, 2001-2014. World J Surg Surgical Res. 2019; 2: 1113.