Journal Basic Info

  • Impact Factor: 1.989**
  • H-Index: 6
  • ISSN: 2637-4625
  • DOI: 10.25107/2637-4625
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Aesthetic & Cosmetic Surgery
  •  Robotic Surgery
  •  Dental Surgery
  •  Surgical Procedures
  •  Cancer Surgery
  •  Hand Surgery
  •  Surgical Oncology
  •  Bariatric Surgery

Abstract

Citation: World J Surg Surg Res. 2022;5(1):1356.DOI: 10.25107/2637-4625.1356

Analysis of SUVmax Metabolic Activity in Non-Small Cell Lung Cancer Depending on Selected Clinical and Pathomorphological Factors

Katarzyna Szwalbe

Department of Thoracic Surgery, General and Oncological Surgery, Medical University of Lodz, Poland

*Correspondance to: Katarzyna Szwalbe 

 PDF  Full Text Research Article | Open Access

Abstract:

Positron Emission Tomography (PET) which uses the phenomenon of increased glucose uptake in tumor cells visible as the focus of abnormal tracer accumulation plays an important role in modern diagnostics of patients with suspected lung cancer. Objective: Analysis of selected clinical and pathomorphological factors that may potentially affect the SUVmax value in patients with Non-Small Cell Lung Cancer (NSCLC). Methodology and Material: The study included 98 patients with confirmed by histopathology NSCLC, who underwent PET examination in preoperative staging. The SUVmax parameter defined by the maximum SUV in one Region of Interest (ROI) voxel was used to assess metabolic activity. Results: A positive correlation was found between the BMI parameter and the SUVmax value (r=0.243) and between SUVmax and primary tumor size (r=0.455). SUVmax was significantly higher in the squamous cell carcinoma group (p<0.001). In the adenocarcinoma group, the SUVmax values were higher in the solid subtype compared to the lepidic subtype (p=0.015). The SUVmax value of poorly differentiated tumors was significantly higher than that of moderately (G2) and well differentiated (G1) tumors (p=0.021; p=0.002). Conclusion: The SUVmax value was statistically higher in squamous cell carcinoma than in adenocarcinoma and in larger diameter tumors. The metabolic activity of PET in the examined histological types depended on the tumor size (T1, T2). The correlation between the size of SUVmax and the type of growth pattern and the histological tumor grade in the adenocarcinoma group was confirmed.

Keywords:

PET; 18F-FDG; Non-small cell lung cancer; SUVmax

Cite the Article:

Szwalbe K. Analysis of SUVmax Metabolic Activity in Non-Small Cell Lung Cancer Depending on Selected Clinical and Pathomorphological Factors. World J Surg Surgical Res. 2022; 5: 1356.

Search Our Journal

Journal Indexed In

Articles with Grants

LAMA1 is a Potential Molecule Associated with Poor Prognosis in Patients with Rectal Adenocarcinoma
 Abstract  PDF  Full Text
Leea indica (Burm.f.) Merr.: A Systematized Acquaint
 Abstract  PDF  Full Text
View More...