Association between Relative Fat Mass and Lumbar Bone Mineral Density in the US Adults: Evidence from National Health and Nutrition Examination Survey (NHANES), 2011 - 2018

Jian Zhang, Yongxin Zhang, Lei Huang, Mangui Li, Huilin Yang and Shunyi Lu

Department of Orthopedic, Zhongshan Hospital, Fudan University, China  Department of Spine and Orthopedic, Tongji Hospital, Tongji University School of Medicine, China  Department of Inspection Section, Qinghai Red Cross Hospital, China  Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, China

^*Correspondance to: Shunyi Lu 

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Abstract:

Relative Fat Mass (RFM) is an innovative obesity metric that provides a more precise evaluation of body fat distribution than conventional methods. This study aims to explore the relationship between RFM and lumbar Bone Mineral Density (BMD) in adults from 2011 to 2018. Weighted multivariate logistic regression, subgroup analysis, and interaction tests were employed to examine the relationship between RFM and lumbar BMD, utilizing data derived from the 2011 to 2018 National Health and Nutrition Examination Survey (NHANES). This study included a total of 11,410 participants. Weighted multiple linear regression analysis revealed a significant negative correlation between RFM and lumbar BMD among adults aged 20 to 59 years. This negative correlation persisted even when RFM was analyzed by quartiles, with individuals in the highest RFM quartile exhibiting lumbar BMD levels 0.046 g/cm2 lower compared to those in the lowest quartile. However, this negative association varied across several specific subgroups. Our findings indicate a significant negative correlation between RFM and lumbar BMD in US adults aged 20-59, offering fresh perspectives and research targets for clinical analysis.

Keywords:

NHANES; Osteoporosis; Lumbar bone mineral density; Relative fat mass

Cite the Article:

Zhang J, Zhang Y, Huang L, Li M, Yang H, Lu S. Association between Relative Fat Mass and Lumbar Bone Mineral Density in the US Adults: Evidence from National Health and Nutrition Examination Survey (NHANES), 2011 - 2018. World J Surg Surgical Res. 2025; 8: 1587..