Journal Basic Info

  • Impact Factor: 1.989**
  • H-Index: 6
  • ISSN: 2637-4625
  • DOI: 10.25107/2637-4625
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Endocrine Surgery
  •  Hepatology
  •  Pediatric Surgery
  •  Transplant Surgery
  •  Anesthesiology
  •  Vascular Surgery
  •  Surgical Procedures
  •  Cardiovascular Surgery


Citation: World J Surg Surg Res. 2021;4(1):1301.DOI: 10.25107/2637-4625.1301

Management of Bilateral Humeral Pathologic Fracture in Metastatic Anaplastic Hemangiopericytoma and Doege- Potter Syndrome: A Case Report and Review of the Literature

Valentina Viscarret1*, Lakshmi Mahali2,3, Harrison Volaski1, Janet Tingling1, Simon Yaguare1, Rui Yang1,3 and David S Geller1,3

1Department of Orthopedic Surgery, Montefiore Medical Center, Bronx, USA
2Department of Endocrinology, Montefiore Medical Center, Bronx, USA
3Albert Einstein College of Medicine, Bronx, USA

*Correspondance to: Valentina Viscarret 

 PDF  Full Text Case Report | Open Access


Background: Solitary Fibrous Tumor/Hemangiopericytoma (SFT/HPC) is a rare, aggressive,
and highly vascularized fibroblastic neoplasm, derived from the pericytes of Zimmerman.
Intracranial anaplastic hemangiopericytoma, a grade III SFT/HPC, has shown high rates of
recurrence and metastasis. Metastasis to bone often leads to pathologic fractures, making careful
surgical management to optimize patient’s quality of life. Bilateral pathologic humeral fracture
is an unusual clinical dilemma and has not been previously reported in the setting of metastatic
anaplastic hemangiopericytoma. The paraneoplastic syndrome known as Doege-Potter syndrome
can additionally complicate management and recognizing this entity is essential. The rarity and
complexity of both clinical presentations warrant a review of the topic.
Case Report: We described a 44-year-old man with widely metastatic intracranial anaplastic
hemangiopericytoma who presented intractable pain in upper extremities and limitation of daily
activities due to bilateral pathologic humeral fracture caused by bone metastasis. In addition, the
orthopedic management was complicated by several episodes of hypoglycemia caused by Doege-
Potter Syndrome. The patient was surgically managed with bilateral humeral intramedullary nail
stabilization and clinically managed with dextrose-containing fluids and prednisone to correct his
Conclusion: Despite the patient’s extremely guarded prognosis, surgical management resulted in
immediate improvement in pain, disability, and quality of life. It is essential for orthopedic surgeons
to be aware that rare paraneoplastic such as Doege-Potter syndrome exists. Attention to the patient’s
preoperative laboratory values, the medical assessment, and the patient’s medical history is all
important and can help prevent perioperative complications and avoidable morbidity.


Anaplastic hemangiopericytoma; Solitary fibrous tumor; Bilateral pathologic humeral fracture; Bone metastasis; Doege-Potter syndrome

Cite the Article:

Viscarret V, Mahali L, Volaski H, Tingling J, Yaguare S, Yang R, et al. Management of Bilateral Humeral Pathologic Fracture in Metastatic Anaplastic Hemangiopericytoma and Doege-Potter Syndrome: A Case Report and Review of the Literature. World J Surg Surgical Res. 2021; 4:1301..

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