Use of Prevena Incision Management System for the Prevention of Surgical Site Infection in Hepatopancreatobiliary Patients

Xin Yi Tan, Shu Yun Heng and Yong Xian Thng

Department of General Surgery, Ng Teng Fong General Hospital, 1 Jurong East Street 21, Singapore

^*Correspondance to: Thng Yong Xian 

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Abstract:

Background: Closed incision negative pressure therapy has been shown to be effective in the prevention of surgical site infection across many surgical disciplines. This study aims to evaluate whether negative pressure wound therapy reduces risks of surgical site infection in hepatopancreatobiliary patients. Methods: This is a retrospective cohort study of 70 patients who underwent hepatopancreatobiliary surgery at a single tertiary care institution from 1 January 2020 to 13 June 2022. Univariate and multivariable logistic analyses were performed to assess the association between surgical site infection and type of wound dressing (Prevena vs standard dressing) with baseline demographics, clinical variables. Statistical significance was set at p≤0.05. Results: In our multivariable analysis of 70, patients with Prevena had a lower risk of surgical site infection [odds ratio (OR)=0.03, 95% confidence interval (CI)=0.001-0.57, p=0.020)]. Patients with operation duration greater than 8 hours had a higher risk of surgical site infection [odds ratio (OR)=7.63, 95% confidence interval (CI)=1.62-35.71, p=0.010)] after adjusting for baseline demographics and clinical variables. Conclusion: The use of Prevena negative pressure dressing was associated with a significant decrease in the risk of surgical site infection in hepatopancreatobiliary patients. This therapy is promising in the prevention of surgical site infection and serves as a tool to mitigate the effects of long surgery in hepatopancreatobiliary patients.

Keywords:

Closed incision negative pressure therapy; Prevena; Surgical site infection; Quality improvement; Hepatopancreatobiliary surgery

Cite the Article:

Xin Yi Tan, Shu Yun Heng, Yong Xian Thng. Use of Prevena Incision Management System for the Prevention of Surgical Site Infection in Hepatopancreatobiliary Patients. World J Surg Surgical Res. 2025; 8: 1601..