Outcome Analysis of Day 4 Embryo Transfer During Fresh Cycle in Assisted Reproductive Technology: A Retrospective Analysis

Yang X, Lian J, Cheng Z and Zhang H

Reproductive Medicine Center, Hangzhou Women’s Hospital, China Prenatal Diagnosis Center, Hangzhou Women’s Hospital, China

^*Correspondance to: Zhaojun Cheng 

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Abstract:

Objective: Clinical outcomes of Day 4 transfer cycles in fresh cycles were followed up to explore the feasibility of Day 4 embryo transfer in fresh cycles. Methods: This study retrospectively counted infertile patients who underwent fresh cycle transfer at Hangzhou Women's Hospital from January 1st, 2019 to December 31st, 2021. The embryos were grouped according to the embryonic age and divided into Day 3 and Day 4 groups. Analyzed differences in general, of infertility factors, the average number of eggs obtained, the average number of embryos transferred, clinical pregnancy outcomes and birth weight of newborns. Results: There was a no difference in clinical data of average age, average years of infertility, average blood AMH value, percentage of primary infertility, endometrial thickness on the day of transplantation, and infertility factors in both groups (p>0.05). Differences in the average number of eggs obtained between groups D3 and D4 (p>0.044). However, there was no statistical differences in the average number of embryos transferred, clinical pregnancy rate, implantation rate, multiple birth rate, early miscarriage rate, live birth rate, birth weight etc. (p>0.05). Conclusion: Transferring Day 4 embryos in a fresh cycle is safe and feasible, and it have similar clinical pregnancy outcomes as Day 3 embryos, but result in a greater chance of transfer than Day 3.

Keywords:

Assisted reproductive technology; Embryo transplantation; Blastocyst culture; Birth follow-up

Cite the Article:

Yang X, Lian J, Cheng Z, Zhang H. Outcome Analysis of Day 4 Embryo Transfer During Fresh Cycle in Assisted Reproductive Technology: A Retrospective Analysis. World J Surg Surgical Res. 2024; 7: 1528..