Treatment of Perianal Fournier’s Gangrene with an Oxygen-Enriched Oil Based Medical Device NOVOX(®) Roll: Case Report

Tommaso Cioppa, Paolo Dreoni, Jacopo Giani, Chiara Linari, Filippo Caminati, Massimo Calistri and Claudio Elbetti

SOSD Proctology “Piero Palagi” Hospital, USL Toscana Centre, Florence, Italy UOC General Surgery “San Giuseppe” Hospital, USL Toscana Centro, Empoli (Florence), Italy

^*Correspondance to: Tommaso Cioppa 

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Abstract:

Background: Fournier’s gangrene is a rare form of necrotizing fasciitis of the perineal, genital or perianal region with high morbidity and mortality rate. Standard treatment is based on medical therapy associated with surgical procedure and postoperative procedures. We report our experience with a new postoperative approach based on advanced dressings performed with NOVOX(®) Roll medical device based on an oxygen-enriched oleic matrix releasing Reactive Oxygen Species (ROS). Case Report: A 75-year-old male patient presented to our clinic with perianal multiple swelling and discoloration associated with fever. CT scan showed the local extension of the complex cellulitis at inferior fascia of the urogenital diaphragm with Colles fascia and the presence of gases in the subcutaneous tissue. Endoanal ultrasound failed to demonstrate evidence of perianal fistula. The patient was treated with early multiple staged large debridement with anal sphincter and scrotum preservation. Close outpatient follow-up was carried out with only advanced dressing performed with Oxygen-Enriched Oil Based Medical Device NOVOX(®) Roll. A complete closure of all lesions was observed. Conclusion: Fournier’s gangrene is a potentially fatal disease that requires a complex and multidisciplinary approach. Our experience with advanced dressing, first reported in the world literature, show that we can considered a new useful approach in the postoperative management of selected patients affected by Fournier’s gangrene. A controlled randomized trial is also required to confirm this evidence.

Keywords:

Fournier’s gangrene; Advanced dressing; NOVOX(®)

Cite the Article:

Cioppa T, Dreoni P, Giani J, Linari C, Caminati F, Calistri M, et al. Treatment of Perianal Fournier’s Gangrene with an Oxygen-Enriched Oil Based Medical Device NOVOX(®) Roll: Case Report. World J Surg Surgical Res. 2022; 5: 1371..