Postoperative Abdominal Adhesions: Pathogenesis and Current Preventive Techniques

Gilberto Guzmán-Valdivia Gómez, Eduardo Tena-Betancourt and Patricio Martínez de Alva Coria

Department of Experimental Surgery, Mexican Medicine School of La Salle University, Mexico

^*Correspondance to: Gilberto Guzmán-Valdivia Gómez 

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Abstract:

Postoperative Abdominal Adhesions (PAA) are a condition that occurs in more than 90% of patients undergoing abdomen surgery, they can cause chronic abdominal pain, female infertility and repeated bowel obstruction, requiring repetitive surgical interventions causing morbidity and mortality, as well as high costs. The formation of the PAA is due to an imbalance between the fibrinogénesis and fibrinolysis in favor of the first, associated with tissue hypoxia secondary to aggression of the peritoneum, also due to the own inflammatory response and the increase in the population of adhesion fibroblasts which inhibit the degradation of the extracellular matrix and facilitate mature collagen and supporting connective tissue. The prevention of adhesions will decrease secondary complications, as well as hospitalizations, unnecessary surgeries and consequently, cost containment.

Keywords:

Postoperative adhesions; Abdominal surgery; Peritoneum

Cite the Article:

Guzmán-Valdivia Gómez G, TenaBetancourt E, de Alva Coria PM. Postoperative Abdominal Adhesions: Pathogenesis and Current Preventive Techniques. World J Surg Surgical Res. 2018; 1: 1008.