Discrepancy in Colorectal Cancer Staging: A Single Center Experience

Elfaedy O, Owens P, Aakif M and Mansour E

Department of Surgery, St. Luke's General Hospital, Ireland

^*Correspondance to: Elfaedy O 

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Abstract:

Background: The TNM (Tumor Node Metastases) staging system developed by the American Joint Committee on Cancer (AJCC) and the Union for International Cancer Control (UICC) is the most widely used classification system for colorectal cancer staging. Accurate predictions of the definitive pathological disease stage using pre-operative clinical-radiological staging techniques are crucial to facilitate timely oncological and surgical planning following diagnosis. Aims: This study describes a cohort of patients treated for colorectal cancer in a general hospital. We aimed to assess the accuracy of pre-operative clinical-radiological staging in predicting pathological colorectal cancer stage at a non-specialist center.
Methods: A retrospective cohort study examined the records of 98 patients with histological confirmed colorectal carcinoma over a 6 year period from 2010 to 2015. Ninety eight patients were treated in St Luke’s General Hospital, while 14 patients were managed and followed up in other hospitals. Data was collected by chart review and from prospectively maintained electronic histopathology and radiology databases.
Results: Ninety eight cases of colorectal cancer were identified. The mean age at presentation was 67.9 years; 50% patients were men; 26.5% had rectal tumors; and 85.7% underwent surgery following clinical staging. Clinical radiological stage and pathological stage differed in 27.4% (n=23) patients (p<0.0001). Of those 23 patients, eight were up staged (none of whom received neoadjuvant therapy), and 15 were down staged post operatively.
Conclusion: Discrepancy in staging colorectal cancer has critical effects on management, outcomes, and survival rates of patients. Appropriate and accurate clinical radiological staging enables multi disciplinary teams to plan optimal management approaches.

Keywords:

Colorectal cancer; Cancer staging; Clinical radiological

Cite the Article:

Elfaedy O, Owens P, Aakif M, Mansour E. Discrepancy in Colorectal Cancer Staging: A Single Center Experience. World J Surg Surgical Res. 2018; 1: 1054.