World J Surg Surg Res | Volume 5, Issue 1 | Research Article | Open Access

Leaks after One Anastomosis Gastric Bypass at Hight Volume Bariatric Centers

Sakran N1,2,3*, Raziel A1, Hod K1, Azaria B1, Goitein D1,4,5#, Kaplan U1,6,7# and Assuta Bariatric Surgeons Collaborative

1Assuta Medical Center, Tel Aviv, Israel 2Department of General Surgery, Holy Family Hospital, Nazareth, Israel 3The Azrieli Faculty of Medicine Safed, Bar-Ilan University, Ramat Gan, Israel 4Department of Surgery C, Sheba Medical Center, Ramat Gan, Israel 5Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel 6Department of Surgery, Emek Medicl Center, Afula, Israel 7Rappaport Faculty of Medicine, Technion, Haifa, Israel

*Correspondance to: Nasser Sakran 

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Background: One Anastomosis Gastric Bypass (OAGB) is rapidly gaining popularity and is now the third most common bariatric procedure performed in the world. Leak remains one of the most dreaded complications after OAGB. Data regarding leaks after OAGB is scary. This study aims to document the incidence, presentation, morbidity, mortality, and management of leaks after OAGB at high-volume bariatric centers. Methods: We collected data from Electronic medical records of all patients who underwent OAGB performed between January 2017 and December 2021 at Assuta Bariatric Centers (ABCs). Data included patients' characteristics, surgical procedure, early postoperative complications, and their classification according to Clavien-Dindo classification. Multivariate logistic regression analysis was performed to identify significant factors contributing to the development of leaks after OAGB. Results: We identified 6,722 patients who underwent a primary (75.9%) or revisional (24.1%) OAGB procedure at ABCs between January 2017 and December 2021. Their preoperative mean age and Body Mass Index (BMI) was 40.6 ± 11.3 years, and 41.2 ± 4.6 kg/m2, respectively, and 75.1% were females. A total of 31 patients (0.46%) developed leaks after OAGB. The most common site was at gastro-jejunal anastomosis (71.0%). The median time for diagnosis was 2 (0 to 14) days. Most cases were treated surgically. Intensive care unit admission post-surgery {Adjusted OR=90.067 [(95% CI: 35.469-228.711), p<0.001]}, Year of operation (2017-2018 vs. 2019-2021) {Adjusted OR=2.965 [(95% CI: 1.399-6.286), p=0.005]} and smoking {Adjusted OR=3.619 [(95% CI: 1.295- 10.11), p=0.014]} were found to be a significant factor for the development of leak post OAGB. Conclusion: The overall rate of leaks after OAGB is very low. Although yet to be established, a learning curve for OAGB need to be established. Postoperative ICU admission and smoking were found to have significant risk factors for the development of leaks post OAGB. Early surgical treatment is the preferred treatment option.


Leak; One anastomosis gastric bypass; Morbid obesity; Postoperative complication


Sakran N, Raziel A, Hod K, Azaria B, Goitein D, Kaplan U, et al. Leaks after One Anastomosis Gastric Bypass at Hight Volume Bariatric Centers. World J Surg Surgical Res. 2022; 5: 1419..

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