Manabu Yasuda1 *, Tomonori Yoshikai2 , Hirofumi Koga3 , Yasuhiro Chikaishi1 , Takashi Iwanami1 and Toshihiro Osaki1
1Department of Chest Surgery, Iizuka Hospital, Japan 2Department of Radiology, Iizuka Hospital, Japan 3Kitakyushu PET Medical Center, JapanFulltext PDF
Background: In this study, we evaluated the activity of IPF on preoperative PET in patients who underwent lung cancer surgery and attempted to identify high-risk patients who might develop postoperative Acute Exacerbation (AE) of IPF. Methods: The pulmonary uptake of Fluorodeoxyglucose (18F-FDG) was quantified at six sites (left and right sides of the upper, middle, and lower lobes), and AE of IPF after lung cancer surgery was examined. Results: UIP patients had a significantly higher FDG distribution in the right upper lobe than other IPs (p<0.05). Seven patients who were all UIP developed AE after lung resection, their FDG accumulation was high in bilateral upper lobe (p<0.05), in UIPs. Conclusion: The widely distributed pulmonary uptake of 18F-FDG on preoperative PET might be an etiologic factor predicting postoperative AE in UIP patients with lung cancer.
Interstitial pneumonia; Positron emission tomography; FDG distribution; Postoperative acute exacerbation
Yasuda M, Yoshikai T, Koga H, Chikaishi Y, Iwanami T, Osaki T. Fluorodeoxyglucose-Positron Emission Tomography Signal Predicts Acute Exacerbation of Interstitial Pneumonia after Lung Cancer Surgery. World J Surg Surgical Res. 2021; 4: 1339..