Does Biopsy Before Partial Nephrectomy Influence the Operative Outcome?

Damien Pasquier1, François Rozet2*, Aude Fregeville3, Eric Barret2, Rafael Sanchez Salas2, Annick Mombet2, Nathalie Cathala2 and Xavier Cathelineau2

1Department of Surgery, Division of Urology, Hospital Center University De Montpellier, University of Montpellier,
France
2Department of Surgery, Division of Urology, Institute Mutualiste Montsouris, University Paris Descartes, France
3Department of Radiology, Institut Mutualiste Montsouris, University Paris Descartes, France

^*Correspondance to: François Rozet 

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Abstract:

Background: Partial Nephrectomy (PN) is the gold standard for patients with cT1 renal lesions.
20% of those lesions are benign. The concordance rate between tumor histotype on percutaneous
Renal Tumor Biopsy (RTB) and on the surgical specimen of the following PN is 90%.
Objective: To evaluate the impact of previous RTB on surgical outcomes and Perioperative
Complications (POC) for PN. Design, setting, and participants: Our study included 164 patients
from the Urology Department of the Paris Institute Mutualiste Montsouris (IMM).
Measurements: Perioperative complications included operative time, clamping time and blood
loss, perioperative complications were assessed by Clavien-Dino classification. In addition, the
histological outcome from RTB and PN were registered.
Results and Limitations: The number of benign lesions differed significantly between patients with
and without prior RTB: respectively 7% (4/56) and 20% (22/107), p=0.03. No significant difference
was found in perioperative complication. No significant difference in Clavien >2 POC rate was
observed with respectively 7% (4/57) and 10% (11/107).
Conclusion: This study shows a significant reduction of benign lesions in PN after RTB. RTB do not
increase the amount or severity of POC.

Keywords:

Benign; Biopsy; Nephrectomy; Renal cell carcinoma; Small renal mass

Cite the Article:

Pasquier D, Rozet F, Fregeville A, Barret E, Salas RS, Mombet A, et al. Does Biopsy Before Partial Nephrectomy Influence the Operative Outcome?. World J Surg Surgical Res. 2021; 4: 1297..