Sentinel Lymph Node Biopsy during Right Hemicolectomy - A Systematic Review

Darren J Porter, Diana Yung and Mark A Potter

Department of Surgery, Ninewells Hospital and Medical School, University of Dundee and Western General Hospital, UK

^*Correspondance to: Darren J Porter 

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Abstract:

Right hemicolectomy and Sentinel Lymph Node Biopsy (SLNB) is an alternative to standard right hemicolectomy with D2 lymphadenectomy. Right hemicolectomy and SLNB may potentially increase lymph node harvest; however current techniques may offer a low sensitivity. The aim of this systematic review was to review the literature in relation to right hemicolectomy and SLNB and compare it’s outcomes to those of standard right hemicolectomy to determine if right hemicolectomy and SLNB could lead to improved patient outcomes in right colonic cancer.
Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed in undertaking this study [14]. MEDLINE was searched to identify all studies describing right hemicolectomy with SLNB from 2008-2018. Statistical analysis was performed using the ‘Meta’ and ‘Metafor’ packages in R statistical software [18,19].
Results: Nine studies with a total of 5096 patients were included in this review of right hemicolectomy with SLNB. SLNB is associated with high lymph node harvests (mean 28.8); however concerns exist regarding its sensitivity in patients with elevated body mass indexes.
Conclusion: Right hemicolectomy with SLNB may upstage and potentially improve prognosis in colorectal cancer, however this procedure may increase patient morbidity and mortality. Further research is necessary to definitively evaluate this technique.

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Cite the Article:

Porter DJ, Yung D, Potter MA. Sentinel Lymph Node Biopsy during Right Hemicolectomy - A Systematic Review. World J Surg Surgical Res. 2019; 2: 1090.